Crique: A System for Automatic Extraction and Formalization of Eligibility Criteria for Clinical Trials

Publikation: Beitrag in Buch/Konferenzbericht/Sammelband/Gutachten › Beitrag in Konferenzband › Beigetragen › Begutachtung

Abstract

Defining formal and structured eligibility criteria for digital recruitment assistant systems can be a challenging interdisciplinary task requiring collaboration between technical and clinical experts. We introduce crique, a free and open source software capable of extracting formal eligibility criteria definitions from study protocols. The extracted eligibility criteria can be exported to OHDSI Atlas and used in conjunction with the standardized OMOP common data model. In this paper, we present our modular process for the extraction of eligibility criteria, describe our implementation in detail, and show examples of extracted eligibility criteria. We conclude with challenges and propose a strategy to evaluate the accuracy of extracted criteria using our software.

Details

OriginalspracheEnglisch
TitelOpening the Personal Gate between Technology and Health Care
Redakteure/-innenMaria Hagglund, Lars Lindskold, Lenka Lhotska, Sara Marceglia, Enea Parimbelli, Lucia Sacchi, Paolo Soda, Lacramioara Stoicu-Tivadar, Pierangelo Veltri, Patrizia Vizza, Mauro Giacomini, Jaime Delgado, Theodoros N. Arvanitis, Elisavet Andrikopoulou, Arriel Benis, Gabriella Balestra, Riccardo Bellazzi, Parisis G. Gallos, Roberto Gatta, Daniele Roberto Giacobbe, Noemi Giordano
Seiten804-808
Seitenumfang5
ISBN (elektronisch)978-1-64368-661-5
PublikationsstatusVeröffentlicht - 21 Mai 2026
Peer-Review-StatusJa

Publikationsreihe

ReiheStudies in health technology and informatics
Band336
ISSN0926-9630

Externe IDs

Scopus 105039957482
ORCID /0000-0002-5002-2676/work/228961604
ORCID /0000-0002-7609-1565/work/228962069

Schlagworte

Schlagwörter

  • Clinical Trials as Topic/methods, Eligibility Determination/methods, Humans, Patient Selection, Software