CD-CODE: crowdsourcing condensate database and encyclopedia

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Nadia Rostam - , Max Planck Institute of Molecular Cell Biology and Genetics, Zentrum für Systembiologie Dresden (CSBD) (Autor:in)
  • Soumyadeep Ghosh - , Max Planck Institute of Molecular Cell Biology and Genetics, Zentrum für Systembiologie Dresden (CSBD) (Autor:in)
  • Chi Fung Willis Chow - , Exzellenzcluster PoL: Physik des Lebens, Max Planck Institute of Molecular Cell Biology and Genetics, Zentrum für Systembiologie Dresden (CSBD) (Autor:in)
  • Anna Hadarovich - , Max Planck Institute of Molecular Cell Biology and Genetics, Zentrum für Systembiologie Dresden (CSBD) (Autor:in)
  • Cedric Landerer - , Max Planck Institute of Molecular Cell Biology and Genetics, Zentrum für Systembiologie Dresden (CSBD) (Autor:in)
  • Rajat Ghosh - , Max Planck Institute of Molecular Cell Biology and Genetics, Zentrum für Systembiologie Dresden (CSBD) (Autor:in)
  • Hong Kee Moon - , Max Planck Institute of Molecular Cell Biology and Genetics (Autor:in)
  • Lena Hersemann - , Max Planck Institute of Molecular Cell Biology and Genetics (Autor:in)
  • Diana M. Mitrea - , Dewpoint Therapeutics (Autor:in)
  • Isaac A. Klein - , Dewpoint Therapeutics (Autor:in)
  • Anthony A. Hyman - , Max Planck Institute of Molecular Cell Biology and Genetics, Zentrum für Systembiologie Dresden (CSBD), Technische Universität Dresden (Autor:in)
  • Agnes Toth-Petroczy - , Max Planck Institute of Molecular Cell Biology and Genetics, Zentrum für Systembiologie Dresden (CSBD), Technische Universität Dresden, Exzellenzcluster PoL: Physik des Lebens (Autor:in)

Abstract

The discovery of biomolecular condensates transformed our understanding of intracellular compartmentalization of molecules. To integrate interdisciplinary scientific knowledge about the function and composition of biomolecular condensates, we developed the crowdsourcing condensate database and encyclopedia (cd-code.org). CD-CODE is a community-editable platform, which includes a database of biomolecular condensates based on the literature, an encyclopedia of relevant scientific terms and a crowdsourcing web application. Our platform will accelerate the discovery and validation of biomolecular condensates, and facilitate efforts to understand their role in disease and as therapeutic targets.

Details

OriginalspracheEnglisch
Seiten (von - bis)673-676
Seitenumfang4
FachzeitschriftNature methods
Jahrgang20 (2023)
Ausgabenummer5
Frühes Online-Datum6 Apr. 2023
PublikationsstatusVeröffentlicht - Mai 2023
Peer-Review-StatusJa

Externe IDs

PubMed 37024650