Coarse Grained Reconfigurable Architectures (CGRAs) have proved to be viable platforms for health monitoring applications. Targeting energy-efficiency, state-of-the-art (SoA) CGRAs are augmented with approximation techniques, while still maintain acceptable accuracy at final Quality of Result (QoR). However, such CGRAs suffer from overheads of collecting separate Add/Mul/Div units. We propose BioCare as an area- and energy-efficient CGRA for health-monitoring edge devices, which exploits the synergistic effects of multiple approximations across HW/SW stack. BioCare offers different levels of energy-accuracy trade-off through the plasticity of its small PEs, each can support precision-adaptability with a Single Instruction, Multiple Data (SIMD) manner. BioCare demonstrates its superiority over SoAs, by achieving up to 32% and 67% area- and energy-savings, with 3.6 χ higher throughput. In addition to analysis on multiple kernels, evaluations on a multi-kernel ECG application shows that BioCare speed-ups the QRS detection latency by 61%, with 0% loss in accuracy. Our implementations will be available at https://cfaed.tu-dresden.de/pd-downloads.