With respect to the politically and socially accelerated transformation towards a bioeconomy, the demand for sustainable materials is put on a new level. To accelerate the laboratory process for the production of pure cellulose mouldings from highly fibrillated wood fibres (FibCell) it is necessary to analyse the impact of all relevant process parameters. Since the production of the mouldings starts from a highly diluted aqueous fibre suspension dewatering trials were carried using DoE. The results clearly show the strong impact of grammage and temperature during the dewatering step and allow to derive optimization means. According to the findings the area of dewatering should be as high as possible and the temperature should be raised up to max. 99 °C. This would reduce filtration resistance and would allow to process cellulose suspensions into mouldings in a far more reasonable way.