No difference in penetrance between truncating and missense/aberrant splicing pathogenic variants in mlh1 and msh2: A prospective lynch syndrome database study

Dominguez-Valentin, M., Plazzer, J. P., Sampson, J. R., Engel, C., Aretz, S., Jenkins, M. A., Sunde, L., & 43 othersBernstein, I., Capella, G., Balaguer, F., Macrae, F., Winship, I. M., Thomas, H., Evans, D. G., Burn, J., Greenblatt, M., de Vos tot Nederveen Cappel, W. H., Sijmons, R. H., Nielsen, M., Bertario, L., Bonanni, B., Tibiletti, M. G., Cavestro, G. M., Lindblom, A., Della Valle, A., Lopez-Kostner, F., Alvarez, K., Gluck, N., Katz, L., Heinimann, K., Vaccaro, C. A., Nakken, S., Hovig, E., Green, K., Lalloo, F., Hill, J., Vasen, H. F. A., Perne, C., Büttner, R., Görgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Hüneburg, R., Doeberitz, M. V. K., Loeffler, M., Rahner, N., Weitz, J., Steinke-Lange, V. & Schmiegel, W., 1 Jul 2021, In: Journal of clinical medicine. 10, 13, 2856.

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Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects

Guo, X., Lin, W., Wen, W., Huyghe, J., Bien, S., Cai, Q., Harrison, T., & 80 othersChen, Z., Qu, C., Bao, J., Long, J., Yuan, Y., Wang, F., Bai, M., Abecasis, G. R., Albanes, D., Berndt, S. I., Bézieau, S., Bishop, D. T., Brenner, H., Buch, S., Burnett-Hartman, A., Campbell, P. T., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Cho, S. H., Conti, D. V., Chapelle, A. D. L., Feskens, E. J. M., Gallinger, S. J., Giles, G. G., Goodman, P. J., Gsur, A., Guinter, M., Gunter, M. J., Hampe, J., Hampel, H., Hayes, R. B., Hoffmeister, M., Kampman, E., Kang, H. M., Keku, T. O., Kim, H. R., Le Marchand, L., Lee, S. C., Li, C. I., Li, L., Lindblom, A., Lindor, N., Milne, R. L., Moreno, V., Murphy, N., Newcomb, P. A., Nickerson, D. A., Offit, K., Pearlman, R., Pharoah, P. D. P., Platz, E. A., Potter, J. D., Rennert, G., Sakoda, L. C., Schafmayer, C., Schmit, S. L., Schoen, R. E., Schumacher, F. R., Slattery, M. L., Su, Y-R., Tangen, C. M., Ulrich, C. M., van Duijnhoven, F. J. B., Van Guelpen, B., Visvanathan, K., Vodicka, P., Vodickova, L., Vymetalkova, V., Wang, X., White, E., Wolk, A., Woods, M. O., Casey, G., Hsu, L., Jenkins, M. A., Gruber, S. B., Peters, U. & Zheng, W., Mar 2021, In: Gastroenterology. 160, 4, p. 1164-1178

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Active remodeling of capillary endothelium via cancer cell-derived MMP9 promotes metastatic brain colonization

Karreman, M. A., Bauer, A. T., Solecki, G., Berghoff, A. S., Mayer, C. D., Frey, K., Hebach, N., & 18 othersFeinauer, M. J., Schieber, N. L., Tehranian, C., Mercier, L., Singhal, M., Venkataramani, V., Schubert, M. C., Hinze, D., Hölzel, M., Helfrich, I., Schadendorf, D., Schneider, S. W., Westphal, D., Augustin, H. G., Goetz, J. G., Schwab, Y., Wick, W. & Winkler, F., 15 Apr 2023, In: Cancer research. 83, 8, p. 1299-1314 16 p.

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Integration of p16/HPV DNA Status with a 24-miRNA-Defined Molecular Phenotype Improves Clinically Relevant Stratification of Head and Neck Cancer Patients

Hess, J., Unger, K., Maihoefer, C., Schüttrumpf, L., Weber, P., Marschner, S., Wintergerst, L., & 23 othersPflugradt, U., Baumeister, P., Walch, A., Woischke, C., Kirchner, T., Werner, M., Sörensen, K., Baumann, M., Tinhofer, I., Combs, S. E., Debus, J., Schäfer, H., Krause, M., Linge, A., von der Grün, J., Stuschke, M., Zips, D., Canis, M., Lauber, K., Ganswindt, U., Henke, M., Zitzelsberger, H. & Belka, C., Aug 2022, In: Cancers. 14, 15, 3745.

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Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity

Möhrmann, L., Werner, M., Oleś, M., Mock, A., Uhrig, S., Jahn, A., Kreutzfeldt, S., & 37 othersFröhlich, M., Hutter, B., Paramasivam, N., Richter, D., Beck, K., Winter, U., Pfütze, K., Heilig, C. E., Teleanu, V., Lipka, D. B., Zapatka, M., Hanf, D., List, C., Allgäuer, M., Penzel, R., Rüter, G., Jelas, I., Hamacher, R., Falkenhorst, J., Wagner, S., Brandts, C. H., Boerries, M., Illert, A. L., Metzeler, K. H., Westphalen, C. B., Desuki, A., Kindler, T., Folprecht, G., Weichert, W., Brors, B., Stenzinger, A., Schröck, E., Hübschmann, D., Horak, P., Heining, C., Fröhling, S. & Glimm, H., 2 Aug 2022, In: Nature communications. 13, 1, p. 4485 4485.

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Validating comprehensive next- generation sequencing results for precision oncology: The NCT/DKTK molecularly aided stratification for tumor eradication research experience

Lier, A., Penzel, R., Heining, C., Horak, P., Fröhlich, M., Uhrig, S., Budczies, J., & 37 othersKirchner, M., Volckmar, A. L., Hutter, B., Kreutzfeldt, S., Endris, V., Richter, D., Wolf, S., Pfütze, K., Neumann, O., Buchhalter, I., de Oliveira, C. M. M., Singer, S., Leichsenring, J., Herpel, E., Klauschen, F., Jost, P. J., Metzeler, K. H., Schulze-Osthoff, K., Kopp, H. G., Kindler, T., Rieke, D. T., Lamping, M., Brandts, C., Falkenhorst, J., Bauer, S., Schröck, E., Folprecht, G., Boerries, M., von Bubnoff, N., Weichert, W., Brors, B., Lichter, P., von Kalle, C., Schirmacher, P., Glimm, H., Fröhling, S. & Stenzinger, A., 2018, In: JCO precision oncology. 2, p. 1-13 13 p.

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Germline MBD4 deficiency causes a multi-tumor predisposition syndrome

Genomics England Research Consortium, The CORGI Consortium & WGS500 Consortium, 5 May 2022, In: American journal of human genetics. 109, 5, p. 953-960 9 p.

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Prenatal dexamethasone treatment for classic 21-hydroxylase deficiency in Europe

Nowotny, H., Neumann, U., Tardy-Guidollet, V., Faisal Ahmed, S., Baronio, F., Battelino, T., Bertherat, J., & 35 othersBlankenstein, O., Bonomi, M., Bouvattier, C., De la Perrière, A. B., Brucker, S., Cappa, M., Chanson, P., Van der Grinten, H. L. C., Colao, A., Cools, M., Davies, J. H., Dorr, H. G., Fenske, W. K., Ghigo, E., Giordano, R., Gravholt, C. H., Huebner, A., Husebye, E. S., Igbokwe, R., Juul, A., Kiefer, F. W., Leger, J., Menassa, R., Meyer, G., Neocleous, V., Phylactou, L. A., Rohayem, J., Russo, G., Scaroni, C., Touraine, P., Unger, N., Vojtkova, J., Yeste, D., Lajic, S. & Reisch, N., May 2022, In: European journal of endocrinology. 168, 5, p. K17-K24

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Plasticity within aldehyde dehydrogenase-positive cells determines prostate cancer radiosensitivity

Schwarz, F. M., Schniewind, I., Besso, M. J., Lange, S., Linge, A., Patil, S. G., Loeck, S., & 8 othersKlusa, D., Dietrich, A., Voss-Boehme, A., Nowrouzi, A., Krause, M., Dubrovska, A., Kurth, I. & Peitzsch, C., May 2022, In: Molecular cancer research : MCR. 20, 5, p. 794-809 16 p.

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Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study

Collaborators, Dec 2022, In: Scientific reports. 12, 1, 4516.

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