Transplantation of a severely lacerated liver - A case report with review of the literature

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Arianeb Mehrabi - , Universität Heidelberg (Autor:in)
  • Hamidreza Fonouni - , Universität Heidelberg (Autor:in)
  • Rezvan Ahmadi - , Universität Heidelberg (Autor:in)
  • Bruno M. Schmied - , Universität Heidelberg (Autor:in)
  • Sascha A. Müller - , Universität Heidelberg (Autor:in)
  • Thilo Welsch - , Universität Heidelberg (Autor:in)
  • Peter Hallscheidt - , Universität Heidelberg (Autor:in)
  • Martin Zeier - , Universität Heidelberg (Autor:in)
  • Jürgen Weitz - , Universität Heidelberg (Autor:in)
  • Jan Schmidt - , Universität Heidelberg (Autor:in)

Abstract

Using lacerated livers for liver transplantation (LTx) can add an option to the extended donor criteria. We present an LTx case using a severely lacerated liver and review of the literature for reported cases. We used a high-grade lacerated liver from a 19-yr-old brain-dead patient caused by traffic accident. The liver had grade IV and II lacerations in the right and left lobe, respectively. Lacerations were managed by sealants, stitching and perihepatic packing. The liver was transplanted to a 49-yr-old man suffering from hepatocellular carcinoma on hepatitis C-induced liver cirrhosis. The two-yr follow-up was uneventful. All published LTx cases using traumatized livers (n = 18) were analyzed. The liver injury ranged from subcapsular hematoma to deep ruptures. Most reported lacerations were in the right lobe, which were managed by digital compression, suturing, electrocautery, and perihepatic packing. The reported complications were primary non-(18%), or poor function, liver abscess, bilioma, and subhepatic hematoma each in one case (5.5%). Six-month graft and patient survival were 71% and 88%, respectively. With meticulous management lacerated livers can be transplanted successfully. Because of complexity of the management, procurement and transplantation should be done by experienced liver surgeons. These organs are marginal grafts and should be offered to selected patients.

Details

OriginalspracheEnglisch
Seiten (von - bis)321-328
Seitenumfang8
FachzeitschriftClinical Transplantation
Jahrgang23
Ausgabenummer3
PublikationsstatusVeröffentlicht - 2009
Peer-Review-StatusJa
Extern publiziertJa

Externe IDs

PubMed 19537300

Schlagworte

Ziele für nachhaltige Entwicklung

ASJC Scopus Sachgebiete

Schlagwörter

  • Lacerated liver, Liver transplantation, Liver trauma