Life Science Engineering (LSE) focuses on technologies at the interface between the life sciences and engineering. It covers a very broad product spectrum, from the pharmaceutical industry to biotechnology and medical technology. An essential element of LSE research is the high degree of interdisciplinary cooperation. Numerous individual technologies are introduced in this chapter that have been explored, developed and optimized separately so far. At the interfaces of these domains, there is great potential for connecting the two disciplines, but its realization is still a distant goal. These interfaces are the urgently required enablers of biological transformation, which permit the initial interconnection of the different domains. Standardized interfaces between biology and technology must therefore be developed.