Synthesis and characterization of thermosensitive PNIPAM microgels covered with superparamagnetic gamma-Fe2O3 nanoparticles

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Jorge Rubio-Retama - (Autor:in)
  • Nikolaos E. Zafeiropoulos - (Autor:in)
  • Caterina Serafinelli - (Autor:in)
  • Rosana Rojas-Reyna - (Autor:in)
  • Brigitte Voit - , Leibniz-Institut für Polymerforschung Dresden (Autor:in)
  • E. Lopez Cabarcos - (Autor:in)
  • Manfred Stamm - , Leibniz-Institut für Polymerforschung Dresden (Autor:in)

Abstract

In the present study we report a facile and reproducible method of preparing magnetic thermosensitive hybrid material based on P(NIPAM) microgels covered with gamma-Fe2O3 nanoparticles of 6-nm size. The iron oxide nanoparticles provided magnetic response to the microgels. In addition, the presence of the magnetic nanoparticles on the microgels altered their swelling behavior and shifted their volume phase transition temperature to higher values. In particular, for inorganic shells with 18% (w/w) of magnetic nanoparticles the volume phase transition of the microgels was shifted from 36 to 40 degrees C. In contrast, for shells consisting of 38% (w/w) magnetic nanoparticles the volume phase transition of the microgels was almost blocked, thus indicating that the microgel thermal response was strongly affected by the presence of the inorganic nanoparticles. The synthesized thermosensitive magnetic microgels are envisaged to be ideal for potential applications as thermosensitive targeted drug delivery systems.

Details

OriginalspracheEnglisch
Seiten (von - bis)10280-10285
Seitenumfang6
FachzeitschriftLangmuir
Jahrgang23
Ausgabenummer20
PublikationsstatusVeröffentlicht - 25 Sept. 2007
Peer-Review-StatusJa
Extern publiziertJa

Externe IDs

PubMed 17718580
Scopus 35148869644
ORCID /0000-0002-4531-691X/work/148607753

Schlagworte

Schlagwörter

  • Poly(n-isopropylacrylamide), Ph, Temperature, Electrolyte, Particles, Polymers, Latex, Salt