Simulation and development of biomimetic electrospun PCL nanofibrous tympanic membrane implants

Publikation: Beitrag in FachzeitschriftKonferenzartikelBeigetragenBegutachtung

Beitragende

Abstract

Electrospun membranes have a great potential in myringoplasty, as the special microstructure of fibers could be comparable to the fiber structure of the tympanic membrane (TM), thus, making it an potential implant for tympanic membrane reconstruction. In this work, the microscale parameters of the fiber structure were studied in a numerical homogenization procedure. The aim of the investigations was to obtain an implant that has a compromise between acoustic and mechanical properties and which at macroscale is comparable with the human TM. The numerical results were verified with experiments on first samples.

Details

OriginalspracheEnglisch
FachzeitschriftProceedings in applied mathematics and mechanics : PAMM
Jahrgang20
Ausgabenummer1
PublikationsstatusVeröffentlicht - Jan. 2021
Peer-Review-StatusJa

Externe IDs

ORCID /0000-0002-7440-9277/work/142239095
Mendeley 95e32268-f394-3a09-a1e0-43e9d027bb3c
unpaywall 10.1002/pamm.202000100

Schlagworte

Schlagwörter

  • PCL implants, electrospun, nanofibrous, tympanic membrane