Severe allergic reactions to para-phenylenediamine in children and adolescents: Should the patch test concentration of PPD be changed?

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

Abstract

Background: Semipermanent henna tattoos containing para-phenylenediamine (PPD) are a well-known cause of severe contact dermatitis, mainly in children. Another relevant exposure source to PPD are hair dyes, which are increasingly used by children and have also been reported to cause intense facial and scalp dermatitis. German patch test guidelines for children recommend that PPD should only be tested in patients who have had a henna tattoo, and then at a reduced concentration of PPD 0.5 % for 24 hours. Patients and methods: We report on patch test results in four patients, three children and one adolescent, with a history of contact dermatitis to henna tattoos or hair dye. We used the recommended or even lower patch test concentrations of PPD with 24-hours exposure in all patients. Results and conclusion: All patients showed very strong patch test reactions to PPD and cross-reactions to related compounds even after dilution of PPD to as low as 0.05 %. Therefore, we suggest that in children with a history of allergic reactions to this compound, a titration test should be performed beginning at a concentration of maximal 0.05 %. This procedure has also been proposed previously based on a larger cases series in adults.

Titel in Übersetzung
Schwere allergische Reaktion auf Para-Phenylendiamin bei Kindern und Jugendlichen
Muss die Test-Konzentration von PPD angepasst werden?

Details

OriginalspracheEnglisch
Seiten (von - bis)258-263
Seitenumfang6
FachzeitschriftJDDG - Journal of the German Society of Dermatology
Jahrgang10
Ausgabenummer4
PublikationsstatusVeröffentlicht - Apr. 2012
Peer-Review-StatusJa

Externe IDs

Scopus 84859102283
PubMed 21812929

Schlagworte

Schlagwörter

  • children, contact dermatitis, hair dye, henna tattoo, Para-Phenylenediamine, patch test