The diameter distribution of bubbles in foam is one of the most important features in foam-based separation processes like foam fractionation and froth flotation. In this study the bubble size at different radial positions of pneumatically produced foams without coalescence and coarsening of bubbles is investigated in a cylindrical column by employing an invasive sampling probe. It is shown that pronounced differences of the local Sauter-mean diameter of the bubbles can appear in radial direction. Oftentimes a parabolic profile with the largest mean bubble diameter in the center of the column is found. The difference of the Sauter-mean diameter between wall- and center region is in the order of up to 60%. Experiments on foams produced with different spargers, gas flow rates and liquid filling levels reveal that the actual degree of the inhomogeniety depends on the specific bubble size distribution that is produced by the sparger, and becomes more pronounced if the range of bubble diameters in the foam increases. As an explanation for the observations, hydrodynamic interactions in the liquid phase, as well as the behavior of different sized bubbles close to the liquid/foam interface are proposed. The observed existence of local differences of the bubble diameters can have a strong influence the dynamic behavior, like liquid drainage, and measurement methods of pneumatic foams. In particular it can limit the applicability of surface-based bubble size measurements.