In the gallery forests and palm swamps of the Orinoco region of Colombia, fire is present as both an anthropogenic and a natural disturbance. These natural formations are impacted by recurrent fires, which typically originate in the savannas. Although interactions among various factors influence the natural regeneration of the swamp palm Mauritia flexuosa, the role of fire in the dynamics of its communities remains unclear. In order to evaluate the post-fire regeneration response of this species, seedlings and fertile individuals, together with its habitat, were mapped in transects across palm swamps in the Vichada Department. Information of the time since last burn was used to establish burning categories (0–2, 2–4, >4 years). The data were processed via Point Pattern Analysis techniques. Effects of distance to mother palm, of microhabitat, and time since last burn were tested using a generalized linear mixed model. The highest regeneration intensities occurred in plots aged 2–4 years since last burn. This range may indicate how fire frequency impacts the regeneration of the species and ecosystems within the savanna landscape. We discuss how fire management and “fire non-suppression”, are related to mitigation actions, including the reduction of greenhouse gas emissions and ecosystem risk impact. Furthermore, we discuss how our results could assist conservation programs and long-term prescribed fire planning in the savannas of the region.