Phase III study of the European Organisation for Research and Treatment of Cancer Quality of Life cancer survivorship core questionnaire

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Marieke van Leeuwen - , Netherlands Cancer Institute (Autor:in)
  • Jacobien M Kieffer - , Netherlands Cancer Institute (Autor:in)
  • Teresa E Young - , East and North Hertfordshire NHS Trust (Autor:in)
  • Maria Antonietta Annunziata - , Unit of Oncological Psychology (Autor:in)
  • Volker Arndt - , Deutsches Krebsforschungszentrum (DKFZ) (Autor:in)
  • Juan Ignacio Arraras - , Hospital Complex of Navarra (HUN) (Autor:in)
  • Didier Autran - , Pôle Neurosciences Cliniques (Autor:in)
  • Hira Bani Hani - , King Hussein Cancer Center (Autor:in)
  • Manas Chakrabarti - , Columbia Asia Hospital (Autor:in)
  • Olivier Chinot - , Pôle Neurosciences Cliniques (Autor:in)
  • Juhee Cho - , Sungkyunkwan University (SKKU) (Autor:in)
  • Rene Aloisio da Costa Vieira - , Hospital de Câncer de Barretos (Autor:in)
  • Anne-Sophie Darlington - , University of Southampton (Autor:in)
  • Philip R Debruyne - , General Hospital Groeninge (Autor:in)
  • Linda Dirven - , Leiden University (Autor:in)
  • Daniela Doege - , Deutsches Krebsforschungszentrum (DKFZ) (Autor:in)
  • Yannick Eller - , University of Dundee (Autor:in)
  • Martin Eichler - , Nationales Centrum für Tumorerkrankungen Dresden (NCT/UCC) (Autor:in)
  • Nanna Fridriksdottir - , Landspitali University Hospital (Autor:in)
  • Ioannis Gioulbasanis - , Larissa General Clinic “E Patsidis” (Autor:in)
  • Eva Hammerlid - , Sahlgrenska University Hospital (Autor:in)
  • Mieke van Hemelrijck - , King's College London (KCL) (Autor:in)
  • Silke Hermann - , Deutsches Krebsforschungszentrum (DKFZ) (Autor:in)
  • Olga Husson - , Institute of Cancer Research (Autor:in)
  • Michael Jefford - , Universitätsklinikum Hamburg-Eppendorf (UKE) (Autor:in)
  • Christoffer Johansen - , University Hospital Southampton NHS Foundation Trust (Autor:in)
  • Trille Kristina Kjaer - , Danish Cancer Society (Autor:in)
  • Meropi Kontogianni - , Harokopio University (Autor:in)
  • Pernilla Lagergren - , Karolinska Institutet (Autor:in)
  • Emma Lidington - , Royal Marsden NHS Foundation Trust (Autor:in)
  • Karolina Lisy - , Universitätsklinikum Hamburg-Eppendorf (UKE) (Autor:in)
  • Ofir Morag - , Maria Sklodowska-Curie Institute of Oncology (Autor:in)
  • Andy Nordin - , East Kent Hospitals University NHS Foundation Trust (Autor:in)
  • Amal S H Al Omari - , King Hussein Cancer Center (Autor:in)
  • Andrea Pace - , IRCCS Istituti fisioterapici ospitalieri - Istituto Regina Elena (Autor:in)
  • Silvia De Padova - , Psycho-Oncology Unit (Autor:in)
  • Duska Petranovia - , University of Rijeka (Autor:in)
  • Monica Pinto - , Rehabilitation Medicine Unit (Autor:in)
  • John Ramage - , Hampshire Hospitals NHS Foundation Trust (Autor:in)
  • Elke Rammant - , King's College London (KCL) (Autor:in)
  • Jaap Reijneveld - , Amsterdam University Medical Centers (UMC) (Autor:in)
  • Samantha Serpentini - , Unit of Psychoncology-Breast Unit (Autor:in)
  • Sam Sodergren - , University of Southampton (Autor:in)
  • Vassilios Vassiliou - , Bank of Cyprus Oncology Centre (Autor:in)
  • Irma Verdonck-de Leeuw - , Monash University (Autor:in)
  • Ingvild Vistad - , Sørlandet Sykehus Kristiansand (Autor:in)
  • Teresa Young - , East and North Hertfordshire NHS Trust (Autor:in)
  • Neil K Aaronson - , Netherlands Cancer Institute (Autor:in)
  • Lonneke V van de Poll-Franse - , Netherlands Cancer Institute (Autor:in)
  • European Organisation for Research and Treatment of Cancer Data Center

Abstract

PURPOSE: The purpose of this study is to develop a European Organisation for Research and Treatment of Cancer Quality of Life Group (EORTC QLG) questionnaire that captures the full range of physical, mental, and social health-related quality of life (HRQOL) issues relevant to disease-free cancer survivors. In this phase III study, we pretested the provisional core questionnaire (QLQ-SURV111) and aimed to identify essential and optional scales.

METHODS: We pretested the QLQ-SURV111 in 492 cancer survivors from 17 countries with one of 11 cancer diagnoses. We applied the EORTC QLG decision rules and employed factor analysis and item response theory (IRT) analysis to assess and, where necessary, modify the hypothesized questionnaire scales. We calculated correlations between the survivorship scales and the QLQ-C30 summary score and carried out a Delphi survey among healthcare professionals, patient representatives, and cancer researchers to distinguish between essential and optional scales.

RESULTS: Fifty-four percent of the sample was male, mean age was 60 years, and, on average, time since completion of treatment was 3.8 years. Eleven items were excluded, resulting in the QLQ-SURV100, with 12 functional and 9 symptom scales, a symptom checklist, 4 single items, and 10 conditional items. The essential survivorship scales consist of 73 items.

CONCLUSIONS: The QLQ-SURV100 has been developed to assess comprehensively the HRQOL of disease-free cancer survivors. It includes essential and optional scales and will be validated further in an international phase IV study.

IMPLICATIONS FOR CANCER SURVIVORS: The availability of this questionnaire will facilitate a standardized and robust assessment of the HRQOL of disease-free cancer survivors.

Details

OriginalspracheEnglisch
Seiten (von - bis)1111-1130
Seitenumfang20
FachzeitschriftJournal of Cancer Survivorship
Jahrgang17
Ausgabenummer4
PublikationsstatusVeröffentlicht - Aug. 2023
Peer-Review-StatusJa

Externe IDs

Scopus 85123960159
WOS 000749103700001
Mendeley dde65402-f9ce-3f2f-8ed9-0d11c7fb44a3
ORCID /0000-0001-9654-2207/work/142254137

Schlagworte

Ziele für nachhaltige Entwicklung

ASJC Scopus Sachgebiete

Schlagwörter

  • Humans, Male, Middle Aged, Quality of Life, Cancer Survivors, Neoplasms/therapy, Survivorship, Surveys and Questionnaires, Disease-free, Survivorship questionnaire, Health-related quality of life, Patient reported outcomes, Oncology, Cancer survivor

Bibliotheksschlagworte