Parosmia in patients with post-infectious olfactory dysfunction in the era of COVID-19-associated olfactory impairment

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Abstract

Objectives: A large number of patients with olfactory impairment are affected by parosmia or phantosmia. This study aimed to examine the demographic and clinical characteristics of parosmia. Methods: We performed a retrospective data analysis of patients consulting at our Smell and Taste Outpatient Clinic. A total of 297 patients were included (203 women, mean age 44.4 ± 13.7 years). Olfactory function was quantified using the “Sniffin’ Sticks” composite TDI (odor threshold, determination, and identification) score. The presence of qualitative olfactory impairment was assessed trough medical history and a parosmia questionnaire. Results: Most of the patients showed olfactory impairment after an infection with SARS-CoV‑2 (84%) and were diagnosed with parosmia (49%). Patients with parosmia (PAR) (n = 201) were significantly younger compared to the group without parosmia (noPAR; n = 92) (PAR 43.2 ± 13 years vs. noPAR 47 ± 15.1 years, p = 0.03) and had a slightly shorter duration of disease, without reaching statistical significance (PAR 10.3 ± 4.9 months, noPAR 13.6 ± 37.6 months, p = 0.23). They also had higher TDI scores (PAR 24.3 ± 7 points, noPAR 21.4 ± 8.2 points, p = 0.003). Conclusions: Patients affected by parosmia were younger and had a better olfactory function compared to patients without parosmia.

Titel in Übersetzung
Parosmie bei Patient:innen mit postinfektiöser Riechstörung in der Ära der COVID-19-assoziierten Riechstörungen

Details

OriginalspracheEnglisch
Seiten (von - bis)649-656
Seitenumfang8
FachzeitschriftHNO
Jahrgang72
Ausgabenummer9
Frühes Online-Datum27 Juni 2024
PublikationsstatusVeröffentlicht - Sept. 2024
Peer-Review-StatusJa

Externe IDs

PubMed 38935276
Scopus 85197909708
ORCID /0000-0001-9713-0183/work/163766504

Schlagworte

Schlagwörter

  • COVID-19, Geruch, Geruchssinn, Olfaction, Olfactory dysfunction, Parosmia, Parosmie, Riechst & ouml;rung, Smell