This tutorial will introduce participants to the Score-P measurement system and the Vampir trace visualization tool for performance analysis. We will provide examples and hands-on exercises covering the full performance engineering workflow cycle on applications that include MPI, OpenMP, and GPU parallelism. Users will learn the following concepts: 1. How to collect an initial profile of their code with Score-P. 2. Evaluation of that profile and its associated measurement overhead. 3. The concepts of scoring and filtering a profile and measurement respectively. 4. How to control the Score-P measurement system via environment variables. 5. How to collect useful traces with acceptable overhead. 6. How to understand trace visualization in Vampir.