Olfactory loss may be a first sign of idiopathic Parkinson's disease
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
Recent studies support the idea of olfactory dysfunction as a very early sign of idiopathic Parkinson's disease (IPD). Aim of the present study was to clinically follow-up patients with idiopathic hyposmia to find out the percentage of patients developing IPD after 4 years time. At baseline, olfactory tests had been combined with transcranial sonography of the substantia nigra and (123)I-FP-CIT SPECT imaging. At the present neurological examination, 7% of the individuals with idiopathic hyposmia had developed clinical IPD. Altogether, 13% presented with abnormalities of the motor system. Our data suggest that a combination of olfactory testing and other tests may constitute a screening tool for the risk to develop IPD.
Details
Originalsprache | Englisch |
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Seiten (von - bis) | 839-842 |
Seitenumfang | 4 |
Fachzeitschrift | Movement Disorders |
Jahrgang | 22 |
Ausgabenummer | 6 |
Publikationsstatus | Veröffentlicht - 30 Apr. 2007 |
Peer-Review-Status | Ja |
Externe IDs
Scopus | 34249051016 |
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Schlagworte
Schlagwörter
- Agnosia/etiology, Follow-Up Studies, Humans, Parkinson Disease/classification, Reagent Kits, Diagnostic, Smell/physiology, Taste, Tomography, Emission-Computed, Single-Photon