Functional electrical stimulation (FES) aims to improve the gait pattern in cases of weak foot dorsiflexion (foot lifter weakness) and, therefore, increase the liveability of people suffering from chronic diseases of the central nervous system, e.g., multiple sclerosis. One important component of FES is the detection of the knee angle in order to enable the situational triggering of dorsiflexion in the right gait phase by electrical impulses. This paper presents an alternative approach to sensors for motion capture in the form of weft-knitted strain sensors. The use of textile-based strain sensors instead of conventional strain gauges offers the major advantage of direct integration during the knitting process and therefore a very discreet integration into garments. This in turn contributes to the fact that the FES system can be implemented in the form of functional leggings that are suitable for inconspicuous daily use without disturbing the wearer unnecessarily. Different designs of the weft-knitted strain sensor and the influence on its measurement behavior were investigated. The designs differed in terms of the integration direction of the sensor (wale- or course-wise) and the width of the sensor (number of loops) in a weft-knitted textile structure.