The Cantabrian Zone, in the Variscan belt of Western Europe, has one of the most continuous Ediacaran–Paleozoic stratigraphic successions in the world. This succession has been extensively studied, including several detrital zircon U–Pb geochronological studies on 30 samples spanning the aforementioned time slice. In this work, we present data from three new samples covering previously unsampled time-slices and perform multidimensional analysis on the 33 samples in order to quantify the similarity/dissimilarity among all of them with the aim of detecting potential changes in source areas through time and the role of recycling. The results indicate a continuous source of sediments from Ediacaran to late Devonian times punctuated by a sudden ephemeral change in the Early Cambrian that can be attributed to local causes during the inception of the Paleozoic passive margin.