Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
This study aimed to build on the relationship of well-established self-report and behavioral assessments to the latent constructs positive (PVS) and negative valence systems (NVS), cognitive systems (CS), and social processes (SP) of the Research Domain Criteria (RDoC) framework in a large transnosological population which cuts across DSM/ICD-10 disorder criteria categories. One thousand four hundred and thirty one participants (42.1% suffering from anxiety/fear-related, 18.2% from depressive, 7.9% from schizophrenia spectrum, 7.5% from bipolar, 3.4% from autism spectrum, 2.2% from other disorders, 18.4% healthy controls, and 0.2% with no diagnosis specified) recruited in studies within the German research network for mental disorders for the Phenotypic, Diagnostic and Clinical Domain Assessment Network Germany (PD-CAN) were examined with a Mini-RDoC-Assessment including behavioral and self-report measures. The respective data was analyzed with confirmatory factor analysis (CFA) to delineate the underlying latent RDoC-structure. A revised four-factor model reflecting the core domains positive and negative valence systems as well as cognitive systems and social processes showed a good fit across this sample and showed significantly better fit compared to a one factor solution. The connections between the domains PVS, NVS and SP could be substantiated, indicating a universal latent structure spanning across known nosological entities. This study is the first to give an impression on the latent structure and intercorrelations between four core Research Domain Criteria in a transnosological sample. We emphasize the possibility of using already existing and well validated self-report and behavioral measurements to capture aspects of the latent structure informed by the RDoC matrix.
Details
Originalsprache | Englisch |
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Seitenumfang | 13 |
Fachzeitschrift | European archives of psychiatry and clinical neuroscience |
Jahrgang | 273 |
Ausgabenummer | 3 |
Publikationsstatus | Veröffentlicht - 2022 |
Peer-Review-Status | Ja |
Externe IDs
PubMed | 35778521 |
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Mendeley | 29aec6ce-0507-3ef2-a5b7-e3e9486d4504 |
WOS | 000819690600001 |
ORCID | /0000-0002-7762-4327/work/141543449 |
ORCID | /0000-0002-2666-859X/work/146643970 |
ORCID | /0000-0002-3415-5583/work/150329688 |
Schlagworte
Ziele für nachhaltige Entwicklung
ASJC Scopus Sachgebiete
Schlagwörter
- Confirmatory factor analysis CFA, Diagnosis and classification, PD-CAN, RDoC, Research Domain Criteria, Transdiagnostic, Pd-can