We study Vehicle to Everything (V2X)-based road traffic safety systems for Vulnerable Road Users (VRUs), particularly focusing on cyclists. The development of Advanced Driver Assistance Systems (ADAS) is usually first done with the help of computer simulation. For VRUs, this lacks suitable mobility models. Furthermore, real-world experimentation is often infeasible due to the immediate danger the test participants would be put into. As a solution, we propose a human-in-the-loop approach. We extended our Virtual Cycling Environment (VCE) to integrate a variety of signals to inform a cyclist riding a real bike on a training stand in a simulated 3D traffic scenario. A particular focus was put on haptic signals, which seem to be best suitable in complex traffic situations.