In this study, the wetting behavior of micro-structured poly(methyl methacrylate) (PMMA) sur-faces produced by plate-to-plate hot embossing is investigated. The embossing tools used consist of stainless steel plates, which were previously processed by different laser methods, namely Direct La-ser Engraving (DLE), Direct Laser Writing (DLW) and Direct Laser Interference Patterning (DLIP). Various textures with spatial periods in the range 1.7 to 900 μm and structure depths between 0.1 and 50 μm were produced and successfully transferred to 175 μm thick PMMA films at an embossing temperature of 130°C. In all cases, the imprints displayed the negative of the stamp textures with a difference between the stamp depth and imprint height between 6 and 16 %. The wetting behavior of the PMMA surfaces was investigated by measuring the static contact angle of distilled water as well as linseed oil. The measurements revealed an increase in the water contact angle from 79° up to 142° on the DLE-based surfaces, whereas for linseed oil, a decrease from 20° to 5° was observed for the same sample. In addition, the PMMA foils were also treated with a hydrophobizing agent in order to modify the surface chemistry.