Improving Blind Spot Denoising for Microscopy
Publikation: Beitrag in Buch/Konferenzbericht/Sammelband/Gutachten › Beitrag in Konferenzband › Beigetragen › Begutachtung
Beitragende
Abstract
Many microscopy applications are limited by the total amount of usable light and are consequently challenged by the resulting levels of noise in the acquired images. This problem is often addressed via (supervised) deep learning based denoising. Recently, by making assumptions about the noise statistics, self-supervised methods have emerged. Such methods are trained directly on the images that are to be denoised and do not require additional paired training data. While achieving remarkable results, self-supervised methods can produce high-frequency artifacts and achieve inferior results compared to supervised approaches. Here we present a novel way to improve the quality of self-supervised denoising. Considering that light microscopy images are usually diffraction-limited, we propose to include this knowledge in the denoising process. We assume the clean image to be the result of a convolution with a point spread function (PSF) and explicitly include this operation at the end of our neural network. As a consequence, we are able to eliminate high-frequency artifacts and achieve self-supervised results that are very close to the ones achieved with traditional supervised methods.
Details
Originalsprache | Englisch |
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Titel | Computer Vision – ECCV 2020 Workshops, Proceedings |
Redakteure/-innen | Adrien Bartoli, Andrea Fusiello |
Herausgeber (Verlag) | Springer Science and Business Media B.V. |
Seiten | 380-393 |
Seitenumfang | 14 |
ISBN (Print) | 9783030664145 |
Publikationsstatus | Veröffentlicht - 2020 |
Peer-Review-Status | Ja |
Extern publiziert | Ja |
Publikationsreihe
Reihe | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
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Band | 12535 LNCS |
ISSN | 0302-9743 |
Konferenz
Titel | Workshops held at the 16th European Conference on Computer Vision, ECCV 2020 |
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Dauer | 23 - 28 August 2020 |
Stadt | Glasgow |
Land | Großbritannien/Vereinigtes Königreich |
Externe IDs
ORCID | /0000-0003-0475-3790/work/161889537 |
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Schlagworte
ASJC Scopus Sachgebiete
Schlagwörter
- CNN, Deconvolution, Denoising, Light microscopy