Implementation of the HOME core outcome set for clinical trials of atopic eczema: barriers and opportunities : the HOME IX meeting report

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Mike E Jacobson - (Erstautor:in)
  • Kim S Thomas - (Autor:in)
  • Christian Apfelbacher - (Autor:in)
  • Yael A Leshem - (Autor:in)
  • Hywel C Williams - (Autor:in)
  • Louise A. A Gerbens - (Autor:in)
  • Phyllis I Spuls - (Autor:in)
  • Jochen Maximilian Schmitt - , Zentrum für evidenzbasierte Gesundheitsversorgung (Autor:in)
  • Laura Howells - (Autor:in)
  • Norito Katoh - (Autor:in)
  • Eric L Simpson - (Letztautor:in)

Abstract

The Harmonising Outcome Measures for Eczema (HOME) initiative established a core outcome set (COS) for atopic eczema (AE) clinical trials in 2019. This set encompasses four core outcome domains and corresponding measurement instruments: clinical signs (EASI), patient-reported symptoms (POEM and NRS 11 point for worst itch over the last 24 h), quality of life (DLQI/CDLQI/IDQoLI), and long-term control (Recap or ADCT). Following its roadmap, the HOME initiative is now focused on supporting implementation of the COS. To identify barriers and facilitators to implementation of the COS, and to guide the effort to promote COS uptake, a virtual consensus meeting was held over 2 days (September 25–26, 2021) attended by 55 participants (26 healthcare professionals, 16 methodologists, 5 patients, 4 industry representatives, and 4 students). Implementation themes were identified by a pre-meeting survey distributed to HOME members, presentations, and whole-group discussion. Participants were divided into five multi-professional small groups which ranked their top 3 most important themes, followed by whole-group discussion and anonymous consensus voting (consensus criteria: < 30% disagreement). Three most important implementation themes were identified and agreed upon: (1) awareness and stakeholder engagement, (2) universal applicability of the COS, and (3) ensuring minimum administrative burden. Working groups to address these issues are now a priority for the HOME initiative. The results from this meeting will inform the development of a HOME Implementation Roadmap in an effort to support other COS groups planning for effective implementation of their core sets.

Details

OriginalspracheEnglisch
Seiten (von - bis)2617-2622
Seitenumfang6
FachzeitschriftArchives of dermatological research
Jahrgang315
Ausgabenummer9
PublikationsstatusVeröffentlicht - Nov. 2023
Peer-Review-StatusJa

Externe IDs

doi 10.1007/s00403-023-02647-w
Scopus 85164779138
Mendeley 9981ccef-54c5-3c81-b971-a0318eeeb54c

Schlagworte

ASJC Scopus Sachgebiete

Schlagwörter

  • Atopic eczema, Core outcome set implementation, Core outcome sets, Harmonising outcome measures for eczema initiative

Bibliotheksschlagworte