How do gravity alterations affect animal and human systems at a cellular/tissue level?

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Francesca Cialdai - , Università degli Studi di Firenze (Autor:in)
  • Austin M. Brown - , Ohio University (Autor:in)
  • Cory W. Baumann - , Ohio University (Autor:in)
  • Debora Angeloni - , Sant'Anna School of Advanced Studies (Autor:in)
  • Sarah Baatout - , Belgian Nuclear Research Center (Autor:in)
  • Alexandra Benchoua - , AFM (Autor:in)
  • Juergen Bereiter-Hahn - , Universitätsklinikum Frankfurt (Autor:in)
  • Daniele Bottai - , Universität Mailand (Autor:in)
  • Judith Irina Buchheim - , Ludwig-Maximilians-Universität München (LMU) (Autor:in)
  • Marco Calvaruso - , National Research Council (IBFM-CNR) (Autor:in)
  • Eugénie Carnero-Diaz - , Sorbonne Université (Autor:in)
  • Sara Castiglioni - , Universität Mailand (Autor:in)
  • Duccio Cavalieri - , Università degli Studi di Firenze (Autor:in)
  • Gabriele Ceccarelli - , University of Pavia (Autor:in)
  • Alexander Choukér - , Ludwig-Maximilians-Universität München (LMU) (Autor:in)
  • Gianni Ciofani - , Italian Institute of Technology (Autor:in)
  • Giuseppe Coppola - , National Research Council of Italy (Autor:in)
  • Gabriella Cusella - , University of Pavia (Autor:in)
  • Andrea Degl’Innocenti - , University of Siena, IIT (Autor:in)
  • Jean Francois Desaphy - , University of Bari (Autor:in)
  • Jean Pol Frippiat - , Université de Lorraine (Autor:in)
  • Michael Gelinsky - , Zentrum für Translationale Knochen-, Gelenk- und Weichgewebeforschung (Autor:in)
  • Giada Genchi - , Italian Institute of Technology (Autor:in)
  • Maria Grano - , University of Bari (Autor:in)
  • Daniela Grimm - , Otto von Guericke University Magdeburg, Universität Aarhus (Autor:in)
  • Alain Guignandon - , Universite Jean Monnet Saint-Etienne (Autor:in)
  • Christiane Hahn - , European Space Agency - ESA (Autor:in)
  • Jason Hatton - , European Space Agency - ESA (Autor:in)
  • Raúl Herranz - , Consejo Superior de Investigaciones Científicas (Autor:in)
  • Christine E. Hellweg - , Deutsches Zentrum für Luft- und Raumfahrt (DLR) e.V. (Autor:in)
  • Carlo Saverio Iorio - , Université libre de Bruxelles (Autor:in)
  • Thodoris Karapantsios - , Aristotle University of Thessaloniki (Autor:in)
  • Jack van Loon - , University of Amsterdam (Autor:in)
  • Matteo Lulli - , Università degli Studi di Firenze (Autor:in)
  • Jeanette Maier - , Universität Mailand (Autor:in)
  • Jos Malda - , Utrecht University (Autor:in)
  • Emina Mamaca - , Institut français de recherche pour l'exploitation de la mer (Autor:in)
  • Lucia Morbidelli - , University of Siena (Autor:in)
  • Angelique van Ombergen - , European Space Agency - ESA (Autor:in)
  • Andreas Osterman - , Ludwig-Maximilians-Universität München (LMU) (Autor:in)
  • Aleksandr Ovsianikov - , Technische Universitat Wien (Autor:in)
  • Francesco Pampaloni - , Universitätsklinikum Frankfurt (Autor:in)
  • Elizabeth Pavezlorie - , Allgemeine Unfallversicherungsanstalt (Autor:in)
  • Veronica Pereda-Campos - , Universite Toulouse III - Paul Sabatier (Autor:in)
  • Cyrille Przybyla - , Université de Montpellier (Autor:in)
  • Christopher Puhl - , Space Applications NV/SA for European Space Agency (Autor:in)
  • Petra Rettberg - , Deutsches Zentrum für Luft- und Raumfahrt (DLR) e.V. (Autor:in)
  • Chiara Risaliti - , Università degli Studi di Firenze (Autor:in)
  • Angela Maria Rizzo - , Universität Mailand (Autor:in)
  • Kate Robson-Brown - , University of Bristol (Autor:in)
  • Leonardo Rossi - , University of Pisa (Autor:in)
  • Giorgio Russo - , National Research Council (IBFM-CNR) (Autor:in)
  • Alessandra Salvetti - , University of Pisa (Autor:in)
  • Daniela Santucci - , Istituto Superiore di Sanita (Autor:in)
  • Matthias Sperl - , Deutsches Zentrum für Luft- und Raumfahrt (DLR) e.V. (Autor:in)
  • Felice Strollo - , IRCCS San Raffaele Pisana - Roma (Autor:in)
  • Kevin Tabury - , Belgian Nuclear Research Center (Autor:in)
  • Sara Tavella - , University of Genoa (Autor:in)
  • Christiane Thielemann - , Aschaffenburg University of Applied Sciences (Autor:in)
  • Ronnie Willaert - , Vrije Universiteit Brussel (Autor:in)
  • Nathaniel J. Szewczyk - , Ohio University (Autor:in)
  • Monica Monici - , Università degli Studi di Firenze (Autor:in)

Abstract

The present white paper concerns the indications and recommendations of the SciSpacE Science Community to make progress in filling the gaps of knowledge that prevent us from answering the question: “How Do Gravity Alterations Affect Animal and Human Systems at a Cellular/Tissue Level?” This is one of the five major scientific issues of the ESA roadmap “Biology in Space and Analogue Environments”. Despite the many studies conducted so far on spaceflight adaptation mechanisms and related pathophysiological alterations observed in astronauts, we are not yet able to elaborate a synthetic integrated model of the many changes occurring at different system and functional levels. Consequently, it is difficult to develop credible models for predicting long-term consequences of human adaptation to the space environment, as well as to implement medical support plans for long-term missions and a strategy for preventing the possible health risks due to prolonged exposure to spaceflight beyond the low Earth orbit (LEO). The research activities suggested by the scientific community have the aim to overcome these problems by striving to connect biological and physiological aspects in a more holistic view of space adaptation effects.

Details

OriginalspracheEnglisch
Aufsatznummer84
Fachzeitschriftnpj Microgravity
Jahrgang9
Ausgabenummer1
PublikationsstatusVeröffentlicht - Dez. 2023
Peer-Review-StatusJa

Externe IDs

ORCID /0000-0001-9075-5121/work/146642759
WOS 001095863600001

Schlagworte

Ziele für nachhaltige Entwicklung

Schlagwörter

  • Space-flight, Microgravity, Inflammation, Metabolism, Virus, Astronauts, Microbiota, Radiation, Endocrine, Responses