As a widely used sheet metal in clinched joints within the automotive industry, the aluminum alloy EN AW-6014 has been the focus of numerous studies. High-cycle fatigue (HCF) is a critical aspect when assessing the durability of clinched joints. In the present work, the HCF behavior of EN AW-6014 T4 was explored both experimentally and numerically. To model the fatigue behavior, Lemaitre’s two-scale damage model was used. Two key parameters, damage strength and damage exponent, are necessary for numerical investigations of HCF behavior. These parameters were determined through experiments with flat specimens and subsequently validated within a numerical model of clinched joints. The numerical results for fatigue match the experimental ones of the clinched joints quite well.