Wearable sensing has recently been highly preferred due to its quick and accurate measurement of physiological parameters. These sensors have been devised using various polymers [1], [2] and nanomaterials [3], [4] suited for the chosen application. With the exponential growth of wearable electronics [5], [6], [7], there is a need to broaden their capabilities in terms of functionality and availability. Commercializing these wearable electronics needs further encouragement to use these sensors as point-of-care devices. Self-powered sensors [8], [9] are one of the growing aspects in the sector of wearable sensing. With the growing requirement for energy usage, self-powered sensing systems need to be developed to generate and harvest energy ubiquitously [10], [11]. This Special Issue highlights some of the published papers that work on using smart textiles and self-powered devices for efficient and sustainable sensing applications.