The hyperfine splitting of the ground state of selected B-like ions within the range of nuclear charge numbers Z=49–83 is investigated in detail. The rigorous QED approach together with the large-scale configuration-interaction Dirac-Fock-Sturm method are employed for the evaluation of the interelectronic-interaction contributions of first and higher orders in 1/Z. The screened QED corrections are evaluated to all orders in αZ by using an effective potential. The influence of nuclear magnetization distribution is taken into account within the single-particle nuclear model.