Scientifically based assessment of possible health risks of mold exposure is very difficult in individual cases and may lead to further questions and uncertainties rather than to valid answers and solutions. To deal with this problem, a series of four workshops was held at the Annual Conferences of the German Society of Hygiene, Environmental Medicine and Preventive Medicine, Germany in 2009, 2010, 2011 and 2012. Frequently asked questions were discussed and answered based on current scientific knowledge. These questions related to possible symptoms, specific symptoms, diseases, diagnostic procedures, therapies, reasonable exposure avoidance, prevention, potential predispositions as well as medical education. Experts and interested parties with different background knowledge worked together to find answers to these questions at the workshops. The results are presented here in detail.