In the medical domain, the use of biocompatible materials, such as titanium or titanium alloys is essential to produce individual implants. As a result of this development, it is now possible to generate new patient-specific geometries fitted to the contour. This paper elucidates the process chain to derive individual design variants and to produce patient-specific bone replacement implants for the lower jaw-bone regions by using innovative reverse engineering and manufacturing methods based on CT-data. For this interdisciplinary project, technical scientists, medical scientists at the university hospital and engineers from a product development firm work together.