Einfluss des therapeutischen Temperaturmanagements auf den klinischen Verlauf bei intrahospital reanimierten Patienten: Eine retrospektive Analyse
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
Methods: Retrospective analysis of all patients with in-hospital cardiac arrest and return of spontaneous circulation (ROSC) in the ICU of the cardiologic department of the University Hospital of Halle (Saale) between 1999 and 2009. Results: During the observation period, 169 patients with in-hospital cardiac arrest and information regarding temperature measurements were treated. Invasive therapeutic temperature management (TTM+) was applied in 64 patients (37.9%), while 105 patients (62.1%) underwent no therapeutic temperature management (TTM−). TTM+ and TTM− showed no relevant differences regarding patient age (TTM+: 67.6 ± 12.6 years; TTM−: 69.8 ± 12.6 years; p = 0.257), comorbidities and the initial rhythm; however, there were more men in the TTM+ group (76.6% vs. 58.1%; p = 0.015). All patients had been intubated. Time until ROSC in TTM+ was significantly longer (25.9 ± 25.8 min vs. 15.0 ± 12.4 min; p < 0.005). TTM+ resulted in a lower 30-day survival and an unfavourable neurologic outcome (Glasgow outcome scale I or II: 75% TTM+ vs. 55.2% TTM−). This negative effect persisted after adjustment for age of the patients, but not after adjustment for age and duration of reanimation (nonadjusted odds ratio for adverse neurologic outcome under TTM+: 0.411 (p = 0.011); odds ratio after adjusting for age: 0.361 (p = 0.09); odds ratio after adjusting for age and duration of the reanimation: 0.505 (p = 0.121)).
Details
Originalsprache | Deutsch |
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Seiten (von - bis) | 297-304 |
Seitenumfang | 8 |
Fachzeitschrift | Medizinische Klinik : Zeitschrift für innere Medizin in Klinik und Praxis |
Jahrgang | 117 |
Ausgabenummer | 4 |
Publikationsstatus | Veröffentlicht - Mai 2022 |
Peer-Review-Status | Ja |
Externe IDs
PubMed | 33877423 |
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Schlagworte
ASJC Scopus Sachgebiete
Schlagwörter
- Body temperature, Heart arrest, Hypothermia, Return of spontaneous circulation, Treatment outcome