Cold denaturation of DNA origami nanostructures
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
The coupling of structural transitions to heat capacity changes leads to destabilization of macromolecules at both elevated and lowered temperatures. DNA origami not only exhibit this property but also provide a nanoscopic observable of cold denaturation processes by directing intramolecular strain to the most sensitive elements within their hierarchical architecture.
Details
Originalsprache | Englisch |
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Seiten (von - bis) | 5590-5593 |
Seitenumfang | 4 |
Fachzeitschrift | Chemical communications |
Jahrgang | 60 |
Ausgabenummer | 43 |
Publikationsstatus | Veröffentlicht - 22 Apr. 2024 |
Peer-Review-Status | Ja |
Externe IDs
PubMed | 38666465 |
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Schlagworte
ASJC Scopus Sachgebiete
Schlagwörter
- DNA/chemistry, Nanostructures/chemistry, Nucleic Acid Denaturation, Cold Temperature, Nucleic Acid Conformation