Changing environments and biomolecule coronas: Consequences and challenges for the design of environmentally acceptable engineered nanoparticles

Publikation: Beitrag in FachzeitschriftÜbersichtsartikel (Review)BeigetragenBegutachtung

Beitragende

  • Marta Markiewicz - , Professur für Hydrochemie und Wassertechnologie, Universität Bremen, Technische Universität Dresden (Autor:in)
  • Jolanta Kumirska - , University of Gdańsk (Autor:in)
  • Iseult Lynch - , University of Birmingham (Autor:in)
  • Marianne Matzke - , Centre for Ecology and Hydrology (Autor:in)
  • Jan Köser - , Universität Bremen (Autor:in)
  • Steve Bemowsky - , Universität Bremen (Autor:in)
  • Dominic Docter - , Universitätsmedizin Mainz (Autor:in)
  • Roland Stauber - , Universitätsmedizin Mainz (Autor:in)
  • Dana Westmeier - , Universitätsmedizin Mainz (Autor:in)
  • Stefan Stolte - , Professur für Hydrochemie und Wassertechnologie, Universität Bremen, Technische Universität Dresden (Autor:in)

Abstract

Nanomaterials (NMs) are gaining increasing commercial importance due to a variety of properties that cannot be achieved with bulk materials. Yet the assessment of their environmental impacts lags behind the technological development. First attempts towards designing inherently safer NMs have been made, yet we are still unable to formulate rules of green nano-design, especially in terms of mitigating (long-term) toxicity and bioaccumulation. Importantly, NMs released to the environment acquire a so called 'environmental corona'-a complex layer of spontaneously adsorbed biomolecules-that significantly impacts their behaviour and fate. This review integrates the current literature on the impact of environmental conditions on NMs fate and behaviour, including corona formation, colloidal stability, reactivity, and toxicty, using a broad range of environmentally relevant NMs. Collectively, components of natural waters (such as salts and/or natural organic matter) often mitigate negative impacts of NMs via different mechanisms including surface passivation and stabilisation against dissolution. The review concludes by discussing some initial strategies on how to rationally design more environmentally acceptable NMs.

Details

OriginalspracheEnglisch
Seiten (von - bis)4133-4168
Seitenumfang36
FachzeitschriftGreen chemistry
Jahrgang20
Ausgabenummer18
PublikationsstatusVeröffentlicht - 2018
Peer-Review-StatusJa

Externe IDs

ORCID /0000-0001-5186-3955/work/165062829

Schlagworte

ASJC Scopus Sachgebiete