BioPAN: a web-based tool to explore mammalian lipidome metabolic pathways on LIPID MAPS.

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

Abstract

Lipidomics increasingly describes the quantitation using mass spectrometry of all lipids present in a biological sample. As the power of lipidomics protocols increase, thousands of lipid molecular species from multiple categories can now be profiled in a single experiment. Observed changes due to biological differences often encompass large numbers of structurally-related lipids, with these being regulated by enzymes from well-known metabolic pathways. As lipidomics datasets increase in complexity, the interpretation of their results becomes more challenging. BioPAN addresses this by enabling the researcher to visualise quantitative lipidomics data in the context of known biosynthetic pathways. BioPAN provides a list of genes, which could be involved in the activation or suppression of enzymes catalysing lipid metabolism in mammalian tissues.

Details

OriginalspracheEnglisch
Aufsatznummer4
Seiten (von - bis)4
FachzeitschriftF1000Research
Jahrgang10
PublikationsstatusVeröffentlicht - Jan. 2021
Peer-Review-StatusJa

Externe IDs

PubMed 33564392
PubMed PMC7848852
Scopus 85100991733

Schlagworte