Associations between tobacco smoking status and patch test results—A cross-sectional pilot study from the Information Network of Departments of Dermatology (IVDK)

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Sonja Molin - , Queen's University Kingston, Ludwig-Maximilians-Universität München (LMU) (Autor:in)
  • Richard Brans - , Universität Osnabrück (Autor:in)
  • Andrea Bauer - , Klinik und Poliklinik für Dermatologie, Universitäts Allergiecentrum, Universitätsklinikum Carl Gustav Carus Dresden (Autor:in)
  • Detlef Becker - , Johannes Gutenberg-Universität Mainz (Autor:in)
  • Burkhard Kreft - , Martin-Luther-Universität Halle-Wittenberg (Autor:in)
  • Vera Mahler - , Friedrich-Alexander-Universität Erlangen-Nürnberg, Paul-Ehrlich-Institut (Autor:in)
  • Christoph Skudlik - , Universität Osnabrück (Autor:in)
  • Rudolf Stadler - , Ruhr-Universität Bochum (Autor:in)
  • Christiane Szliska - , Diakonie Klinikum Bethesda (Autor:in)
  • Elke Weisshaar - , Universität Heidelberg (Autor:in)
  • Johannes Geier - , Georg-August-Universität Göttingen (Autor:in)

Abstract

Background: Earlier studies suggested a potential association between tobacco smoking and nickel sensitization, but little is known about other contact allergens. Objectives: To investigate the association of smoking status and contact sensitizations as well as subtypes of dermatitis, and to analyse the sensitization profiles of tobacco smokers. Patients and Methods: Within the Information Network of Departments of Dermatology (IVDK), we performed a cross-sectional multicentre pilot study comprising 1091 patch-tested patients from 9 departments, comparing 541 patients with a history of cigarette smoking (281 current and 260 former smokers) with 550 never-smokers. Results: We could not confirm the previously reported association between nickel sensitization and tobacco smoking. Moreover, sensitizations to other allergens, including colophony, fragrance mix I, Myroxylon pereirae and formaldehyde, were not increased in cigarette smokers compared with never smokers. Hand dermatitis (50.6% vs. 33.6%) and occupational cause (36.2% vs. 22.5%) were significantly more frequent among cigarette smokers compared with never-smokers as shown by non-overlapping 95% confidence intervals. Conclusions: Although our study does not allow a firm conclusion on whether smoking status contributes to certain contact sensitizations, it confirms an association of smoking with hand dermatitis and occupational cause.

Details

OriginalspracheEnglisch
Seiten (von - bis)203-211
Seitenumfang9
FachzeitschriftContact dermatitis
Jahrgang91
Ausgabenummer3
PublikationsstatusVeröffentlicht - Sept. 2024
Peer-Review-StatusJa

Externe IDs

PubMed 38778718
ORCID /0000-0002-4411-3088/work/169643520

Schlagworte

Schlagwörter

  • allergic contact dermatitis, hand dermatitis, occupational, patch testing, tobacco smoking