Association of household cleaning agents and disinfectants with asthma in young German adults

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Tobias Weinmann - , Ludwig-Maximilians-Universität München (LMU) (Autor:in)
  • Jessica Gerlich - , Ludwig-Maximilians-Universität München (LMU) (Autor:in)
  • Sabine Heinrich - , Ludwig-Maximilians-Universität München (LMU) (Autor:in)
  • Dennis Nowak - , Ludwig-Maximilians-Universität München (LMU) (Autor:in)
  • Erika Von Mutius - , Ludwig-Maximilians-Universität München (LMU) (Autor:in)
  • Christian Vogelberg - , Klinik und Poliklinik für Kinder- und Jugendmedizin, Technische Universität Dresden (Autor:in)
  • Jon Genuneit - , Universität Ulm (Autor:in)
  • Stefanie Lanzinger - , Universität Ulm (Autor:in)
  • Saba Al-Khadra - , Deutsche PalliativStiftung (Autor:in)
  • Tina Lohse - , Universität Zürich (Autor:in)
  • Irina Motoc - , Vrije Universiteit Amsterdam (VU) (Autor:in)
  • Viola Walter - , Deutsches Krebsforschungszentrum (DKFZ) (Autor:in)
  • Katja Radon - , Ludwig-Maximilians-Universität München (LMU) (Autor:in)

Abstract

Objectives: We scrutinised the association of private use of household sprays and disinfectants with asthma incidence in young adults in the transition from school to working life. Methods: Between 2007 and 2009,2051 young adults aged 19-24 years living in two major German cities took part in the Study on Occupational Allergy Risks II. Self-reported exposure to household sprays and disinfectants was characterised according to a composite score for frequency of use as no use (score=0), low use (score between 1 and the median), medium use (score between the median and the 90th percentile) and high use (score above the 90th percentile). Two outcome variables (current asthma and current wheezing) with four mutually exclusive categories (never, incident, persistent and remittent) were used for the risk analyses. Multinomial logistic regression models examined the association between the frequency of using household sprays and disinfectants with asthma and wheezing adjusting for potential confounders. Results: Compared with no use, high use of disinfectants was associated with a more than twofold increased odds of incident asthma (OR 2.79, 95% CI 1.14 to 6.83). In addition, low/medium use of disinfectants was associated with remittent asthma (OR 2.39, 95% CI 1.29 to 4.47). The evidence for an association between high usage of household sprays and asthma incidence was weak (OR 2.79, 95% CI 0.84 to 9.20). Conclusion: Our results support the hypothesis of an association between the use of cleaning products and elevated risks for asthma and wheezing in young adults at the start of working life.

Details

OriginalspracheEnglisch
Seiten (von - bis)684-690
Seitenumfang7
FachzeitschriftOccupational and Environmental Medicine
Jahrgang74
Ausgabenummer9
PublikationsstatusVeröffentlicht - Sept. 2017
Peer-Review-StatusJa

Externe IDs

Scopus 85027543999
PubMed 28483971

Schlagworte

Schlagwörter

  • asthma, disinfectants, sprays, wheezing, young adults