As guidance for informed decision-making, we estimated the environmental burden of disease attributable to road-traffic noise in Hesse. Using detailed road-traffic-noise exposure data provided by HLNUG, we calculated the DALYs due to road-traffic noise > 40 dB(A) L24h (unweighted average 24 h noise level) and other noise metrics for endpoints with known dose-response functions and evidence in the literature (NORAH-study on disease risks and WHO reviews). For Hesse, we found a total of 26,501 DALYs attributable to road-traffic noise or 435 DALY per 100,000 persons for the reference year, 2015. The end points "Annoyance" and "Sleep disturbance" contribute more than 70 % of the burden. Further, we estimated that a hypothetic uniform road-traffic-noise reduction of 3 dB would prevent 23% of this burden of disease. We are planning to suggest an alternative approach to extract an annoyance function from raw data used in the WHO-review. Our findings imply that the burden attributable to street-traffic-noise is of the same order of magnitude as, for example, the more fully researched environmental risk factor particulate matter. HLNUG is evaluating expanding the BoD-approach including uncertainty assessment to other environmental risk factors and its use for informing decision makers.