Antibiotic Stewardship (ABS). Teil 1: Grundlagen

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung


  • S. Wendt - , Universität Leipzig (Autor:in)
  • D. Ranft - , Universität Leipzig (Autor:in)
  • K. de With - , Klinische Infektiologie, Universitätsklinikum Carl Gustav Carus Dresden (Autor:in)
  • W. V. Kern - , Albert-Ludwigs-Universität Freiburg (Autor:in)
  • B. Salzberger - , Universität Regensburg (Autor:in)
  • C. Lübbert - , Universität Leipzig (Autor:in)


Against the background of increasing antimicrobial resistance, antibiotic stewardship (ABS) is an important measure to counteract the spread of resistant pathogens and multidrug resistance. For Germany and Austria, a comprehensive S3 guideline is available, which was last updated in 2018. The control of antibiotic or anti-infective use in hospitals should be guided by specialized ABS teams. At the hospital level, ABS also includes a structured ongoing analysis of local antibiotic use and resistance data. Recommendations for locally adapted therapy regimens should be derived and implemented from this data analysis. ABS consists of regular ward rounds (“ABS visits”), during which members of the ABS team review the indication, dosage, route of administration and duration of antimicrobial therapy at the bedside. Here, the key challenge is to save antibiotics without compromising the individual patient. Digitalization and artificial intelligence offer new options for ABS, while the adaption of inpatient concepts to outpatient care is also important.


Seiten (von - bis)375-387
FachzeitschriftDer Internist
PublikationsstatusVeröffentlicht - 1 Apr. 2020

Externe IDs

PubMed 32144476
ORCID /0000-0001-9473-3018/work/148606207


ASJC Scopus Sachgebiete


  • Anti-bacterial agents, Anti-infective agents, Antimicrobial stewardship, Drug resistance, microbial, Evidence-based practice, Guideline, Resources