Advanced light microscopy core facilities: Balancing service, science and career

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung


  • The German Bioimaging Network - (Autor:in)
  • Core Facility Lichtmikroskopie
  • University of Konstanz
  • Universität Heidelberg
  • Universitätsklinikum Frankfurt
  • Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)
  • Max Planck Institute for Biology of Ageing
  • Max Planck Institute of Molecular Cell Biology and Genetics
  • Max Planck Institute for Developmental Biology
  • European Molecular Biology Laboratory (EMBL) Heidelberg
  • Deutsche Zentrum für Infektionsforschung
  • Max-Delbrück-Centrum für Molekulare Medizin (MDC)
  • Heinrich Heine Universität Düsseldorf
  • Universität zu Köln
  • Leibniz Institute for Neurobiology
  • Max Planck Institute of Immunobiology and Epigenetics


Core Facilities (CF) for advanced light microscopy (ALM) have become indispensable support units for research in the life sciences. Their organizational structure and technical characteristics are quite diverse, although the tasks they pursue and the services they offer are similar. Therefore, throughout Europe, scientists from ALM-CFs are forming networks to promote interactions and discuss best practice models. Here, we present recommendations for ALM-CF operations elaborated by the workgroups of the German network of ALM-CFs, German Bio-Imaging (GerBI). We address technical aspects of CF planning and instrument maintainance, give advice on the organization and management of an ALM-CF, propose a scheme for the training of CF users, and provide an overview of current resources for image processing and analysis. Further, we elaborate on the new challenges and opportunities for professional development and careers created by CFs. While some information specifically refers to the German academic system, most of the content of this article is of general interest for CFs in the life sciences. Microsc. Res. Tech. 79:463-479, 2016.


Seiten (von - bis)463-479
FachzeitschriftMicroscopy research and technique
PublikationsstatusVeröffentlicht - 4 Apr. 2016

Externe IDs

PubMed 27040755
ORCID /0000-0002-7133-7474/work/142251278


DFG-Fachsystematik nach Fachkollegium


  • Core facility administration, Instrument performance tests, Microscopy room requirements, User and staff training, User/staff/instrument ratio