Adolescent to young adult longitudinal development across 8 years for matching emotional stimuli during functional magnetic resonance imaging

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung



We investigated development from adolescence to young adulthood of neural bottom-up and top-down processes using a functional magnetic resonance imaging task on emotional attention. We followed 249 participants from age 14-22 in up to four waves resulting in 687 total scans of a matching task in which participants decided whether two pictures were the same including distracting emotional or neutral scenes. We applied generalized additive mixed models and a reliability approach for longitudinal analysis. Reaction times and error rates decreased longitudinally. For top-down processing, we found a longitudinal increase for the bilateral inferior frontal gyrus (IFG) for negative stimuli and in the left IFG also for positive and neutral stimuli. For bottom-up activation in the bilateral amygdala, we found a relative stability for negative and neutral stimuli. For positive stimuli, there was an increase starting in the twenties. Results show ongoing behavioral and top-down prefrontal development relatively independent from emotional valence. Amygdala bottom-up activation remained stable except for positive stimuli. Current findings add to the sparse literature on longitudinal top-down and bottom-up development into young adulthood and emphasize the role of reliability. These findings might help to characterize healthy in contrast to dysfunctional development of emotional attention.


Seiten (von - bis)101131
FachzeitschriftDevelopmental cognitive neuroscience
Frühes Online-Datum3 Juli 2022
PublikationsstatusVeröffentlicht - Okt. 2022

Externe IDs

PubMedCentral PMC9352466
ORCID /0000-0001-6482-1316/work/143782475
ORCID /0000-0003-1477-5395/work/143783490
Scopus 85134895018
ORCID /0000-0001-5398-5569/work/150329509
ORCID /0000-0002-8493-6396/work/150330242