Active T1 transitions in cellular networks

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Charlie Duclut - , Max-Planck-Institute for the Physics of Complex Systems (Autor:in)
  • Joris Paijmans - , Max-Planck-Institute for the Physics of Complex Systems (Autor:in)
  • Mandar M. Inamdar - , Indian Institute of Technology Bombay (IITB) (Autor:in)
  • Carl D. Modes - , Max Planck Institute of Molecular Cell Biology and Genetics, Zentrum für Systembiologie Dresden (CSBD), Technische Universität Dresden, Exzellenzcluster PoL: Physik des Lebens (Autor:in)
  • Frank Jülicher - , Max-Planck-Institute for the Physics of Complex Systems, Zentrum für Systembiologie Dresden (CSBD), Technische Universität Dresden, Exzellenzcluster PoL: Physik des Lebens (Autor:in)

Abstract

Abstract: In amorphous solids as in tissues, neighbor exchanges can relax local stresses and allow the material to flow. In this paper, we use an anisotropic vertex model to study T1 rearrangements in polygonal cellular networks. We consider two different physical realizations of the active anisotropic stresses: (i) anisotropic bond tension and (ii) anisotropic cell stress. Interestingly, the two types of active stress lead to patterns of relative orientation of T1 transitions and cell elongation that are different. Our work suggests that these two realizations of anisotropic active stresses can be observed in vivo. We describe and explain these results through the lens of a continuum description of the tissue as an anisotropic active material. We furthermore discuss the energetics of the dynamic tissue and express the energy balance in terms of internal elastic energy, mechanical work, chemical work and heat. This allows us to define active T1 transitions that can perform mechanical work while consuming chemical energy. Graphic abstract: [Figure not available: see fulltext.]

Details

OriginalspracheEnglisch
Aufsatznummer29
FachzeitschriftEuropean Physical Journal E
Jahrgang45
Ausgabenummer3
PublikationsstatusVeröffentlicht - März 2022
Peer-Review-StatusJa

Externe IDs

PubMed 35320447