A Phase Field Approach to Trabecular Bone Remodeling
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
We introduce a continuous modeling approach which combines elastic response of the trabecular bone structure with the concentration of signaling molecules within the bone and a mechanism for concentration dependent local bone formation and resorption. In an abstract setting bone can be considered as a shape changing structure. For similar problems in materials science phase field approximations have been established as an efficient computational tool. We adapt such an approach for trabecular bone remodeling. It allows for a smooth representation of the trabecular bone structure and drastically reduces computational costs if compared with traditional micro finite element approaches. We demonstrate the advantage of the approach within a minimal model. We quantitatively compare the results with established micro finite element approaches on simple geometries and consider the bone morphology within a bone segment obtained from μCT data of a sheep vertebra with realistic parameters.
Details
Originalsprache | Englisch |
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Aufsatznummer | 12 |
Fachzeitschrift | Frontiers in applied mathematics and statistics |
Jahrgang | 6 |
Publikationsstatus | Veröffentlicht - 5 Mai 2020 |
Peer-Review-Status | Ja |
Externe IDs
Scopus | 85085109851 |
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Schlagworte
ASJC Scopus Sachgebiete
Schlagwörter
- bone remodeling, mechanosensing, phase-field, topology optimization, trabecular bone