One of the most common causes of death from cancer for both women and men is lung cancer. Lung nodules are critical for the screening of cancer and early recognition permits treatment and enhances the rate of rehabilitation in patients. Although a lot of work is being done in this area, an increase in accuracy is still required to swell patient persistence rate. However, traditional systems do not segment cancer cells of different forms accurately and no system attained greater reliability. An effective screening procedure is proposed in this work to not only identify lung cancer lesions rapidly but to increase accuracy. In this procedure, Otsu thresholding segmentation is utilized to accomplish perfect isolation of the selected area, and the cuckoo search algorithm is utilized to define the best characteristics for partitioning cancer nodules. By using a local binary pattern, the relevant features of the lesion are retrieved. The CNN classifier is designed to spot whether a lung lesion is malicious or non-malicious based on the retrieved features. The proposed framework achieves an accuracy of 96.97% percent. The recommended study reveals that accuracy is improved, and the results are compiled using Particle swarm optimization and genetic algorithms.