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Strukturelle Bioinformatik (FoG)

Organisation: Forschungs-/Arbeitsgruppe


Our group develops and applies computational strategies appplied to rational engineering and de novo design for target/drug discovery and biotechnology innovation.
By applying structure-based computational methods, molecular modeling and computer simulation techniques, and in very close collaboration with experimentalists, we try to decipher the relationships between biomolecular structure and function in order to understand the molecular basis of protein/DNA/other recognition, which will allow us to rationally intervene their biological function. Our current research focuses on the discovery and functional characterization of novel proteins, the rational engineering of proteins with improved functional properties, and de novo design of molecular scaffolds for a variety of biotechnological and biomedical applications.


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