Stability of lipid domains
Research output: Contribution to journal › Review article › Contributed › peer-review
Contributors
Abstract
Membranes with simple lipid composition exhibit complex phase behavior. Ordered and disordered liquid phases can coexist in cholesterol-containing membranes with lipid compositions resembling biological membranes and at physiological temperatures. Research during the last years suggests that these lipid domains play a role in the organization of biological membranes. Understanding the principles that govern the formation and stability of lipid domains is of great importance to build a model that properly describes membrane structure and function. In this review, we describe the current knowledge of the chemical and physical basis of lipid domains and its application to biological membranes.
Details
Original language | English |
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Pages (from-to) | 1653-1658 |
Number of pages | 6 |
Journal | FEBS letters |
Volume | 584 |
Issue number | 9 |
Publication status | Published - May 2010 |
Peer-reviewed | Yes |
External IDs
PubMed | 20036662 |
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Keywords
ASJC Scopus subject areas
Keywords
- Cholesterol, Line tension, Lipid-lipid interaction, Liquid ordered phase, Sphingolipid