Non-additive coupling enables propagation of synchronous spiking activity in purely random networks

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Raoul Martin Memmesheimer - , Radboud University Nijmegen (Author)
  • Marc Timme - , Max Planck Institute for Dynamics and Self-Organization, Bernstein Center for Computational Neuroscience Göttingen (Author)

Abstract

Despite the current debate about the computational role of experimentally observed precise spike patterns it is still theoretically unclear under which conditions and how they may emerge in neural circuits. Here, we study spiking neural networks with non-additive dendritic interactions that were recently uncovered in single-neuron experiments. We show that supra-additive dendritic interactions enable the persistent propagation of synchronous activity already in purely random networks without superimposed structures and explain the mechanism underlying it. This study adds a novel perspective on the dynamics of networks with nonlinear interactions in general and presents a new viable mechanism for the occurrence of patterns of precisely timed spikes in recurrent networks.

Details

Original languageEnglish
Article numbere1002384
JournalPLOS computational biology
Volume8
Issue number4
Publication statusPublished - 19 Apr 2012
Peer-reviewedYes
Externally publishedYes

External IDs

PubMed 22532791
ORCID /0000-0002-5956-3137/work/142242491