Influence of the Maillard Reaction on the Allergenicity of Food Proteins and the Development of Allergic Inflammation
Research output: Contribution to journal › Review article › Contributed › peer-review
Contributors
Abstract
Purpose of ReviewThe Maillard reaction (MR) is a non-enzymatic reaction between reducing sugars and compounds with free amino groups such as proteins and takes place during thermal processing and storage of foods. This review aims to discuss potential effects of dietary MR products on the pathological mechanisms of allergic diseases.Recent FindingsSince the MR leads to modification of proteins with various types of glycation structures, the impact of the MR on the immunogenicity and potential allergenicity of food proteins in many allergenic foods has been assessed. In addition, recent studies have suggested that the MR products, in particular advanced glycation end products (AGEs), contained in the diet may be involved in the development of chronic inflammation by acting as inflammatory components and affecting the gut microbiome.SummaryThis review found that the biological, immunological, and allergic properties of dietary MR products are diverse due to the complexity of the MR.
Details
Original language | English |
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Article number | 4 |
Number of pages | 7 |
Journal | Current allergy and asthma reports |
Volume | 19 |
Issue number | 1 |
Publication status | Published - Jan 2019 |
Peer-reviewed | Yes |
Externally published | Yes |
External IDs
Scopus | 85060647544 |
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ORCID | /0000-0001-8528-6893/work/142256502 |
Keywords
Keywords
- Maillard reaction, Food allergens, Advanced glycation end products (AGEs), Pattern recognition receptors, Gut microbiome, GLYCATION END-PRODUCTS, CHAIN FATTY-ACIDS, RAGE, RECEPTOR, ENDPRODUCTS, MICROBIOME, DISEASE, DIVERSITY, STABILITY, MODULATE