Subjective Triggering Conditions of Affective Episodes in Adolescents and Young Adults from the General Population.

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Beitragende

Abstract

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Introduction: Affective episodes often emerge in adolescence and young adulthood. Identification of factors subjectively
associated with their onset may improve aetiological models and targeted intervention.
Objectives: To examine precipitating conditions of (hypo-)manic and depressive episodes in adolescents and young
adults from the general population.
Methods: A random sample of 14-21 year-olds was drawn from the population registry of Dresden, Germany, and
N=1180 were assessed in 2015/2016 (response rate: 21.7%). Lifetime depressive and (hypo-)manic symptoms as well as
full-threshold depressive and (hypo-)manic episodes (DSM-5) were identified using standardized interview. Participants
reporting depressive or (hypo-)manic symptoms were asked whether and which events or conditions they associate with
episode onset. Besides responses on a list providing potential triggering conditions a free answer was possible.
Qualitative content analysis preceded quantitative logistic regression analyses (significance level p<.05). Considered
categories were: negative life events (further divided for depression into loss/danger events, burdensome life conditions,
and interpersonal factors), events requiring adaptation, positive life events, internal factors, and other factors.
Results: The vast majority of participants reporting depressive (n=682) respectively (hypo-)manic (n=200) symptoms also
reported a precipitating condition (94.7%, 83.1%). There was no significant association between any triggering condition
and the occurrence of a full-threshold depressive (n=206) or (hypo-)manic (n=25) episode. However, the number of
reported categories of precipitating conditions was associated with full-threshold depressive and (hypo-)manic episodes.
Among those with depressive or (hypo-)manic symptoms and at least one reported precipitating condition, multiple
regression models including all condition categories showed that in particular internal factors, interpersonal problems and
other factors were associated with the occurrence of a full-threshold depressive episode (n=199) and positive life events
as well as internal factors were associated with the occurrence of a full-threshold (hypo-)manic episode (n=21).
Conclusions: Adolescents and young adults from the general population usually associate the onset of phases with
affective symptoms with precipitating conditions but these do not necessarily signal the emergence of a diagnostically
relevant episode. Nevertheless, a greater number of and the presence of particular precipitating conditions may indicate
the emergence of full-blown depressive or (hypo-)manic episodes. Thus, asking for subjective triggers appears relevant
and may guide early identification and intervention.
Disclosure of Interest: None Declared

Details

OriginalspracheEnglisch
PublikationsstatusVeröffentlicht - 25 März 2023
Peer-Review-StatusJa

Konferenz

Titel31st European Congress of Psychiatry (EPA)
KurztitelEPA
Veranstaltungsnummer
Dauer25 - 28 März 2023
BekanntheitsgradInternationale Veranstaltung
Ort
StadtParis
LandFrankreich

Externe IDs

ORCID /0000-0002-9687-5527/work/142235273

Schlagworte